The gastric secretion mechanism and the factors related to the formation of the peptic ulcer are important aspects for the medicine development new that can act as antagonistic in these processes. The used medicines as citoprotetores tend to increase the resistance of the gastric mucosa and to diminish the harmful agents (CAVALINI, 2005). 3.3. Mechanisms of gastric protection Physiological, the aggressive and protective agents of the gastric mucosa are in balance. The concentration of H+ in the lumen of the stomach is raised, however, mechanisms exist that hinder its return for the gastric cells. Amongst the protective mechanisms it is to the stimulation of the mucous cells, for the Ach, for protective release of muco (MILK, 2004).
The electric resistance of the membrane of the epithelial cells, the high cellular junctions and the negative electric potential of the way hinder the passive ticket them ons H+ through the cellular membranes. The defense of the gastric mucosa is based on three main mechanisms: humorais (release of E2 Prostaglandin) and nitric oxide (IN), neural (sensorial neurons) and functionaries (secretion of muco, motilidade and microcirculation) (RODRIGUES, 2008). The mucous cells liberate muco protective, forming viscous, transparent, adherent and elastic a system (95% water and 5% glycoproteins). Muco recovers the fabric gastric, acting as a sweeper of free radicals, aid in cellular regeneration and the cicatrizao of ulcerativas injuries (RODRIGUES, 2008). The barrier muco-bicarbonate-fosfolipdios hinders the installation of microorganisms, making physical protection against foods and acts as a powerful lubricant (ROZZA, 2009).
In the interior of the cells of the mucosa, the oxidation-reduction system functions (redox), that it acts as a citoprotetor system. The free radicals are formed physiological and in inflammatory processes, then, the system redox if it becomes essential for the reduction of less reactive free radicals ons, increasing the cellular protection (MAYER, 2007).
The joined results show that for the most part of the users acometidos for the IRC taken care of in the sector of hemodilise of a hospital of the city of Cricima- SC they are of the masculine sex. In accordance with some authors, the IRC acomete patient with age enters the 40 60 years and has short while bigger incidence between men of what in mulheres3,6. In studies carried through for other authors, about 53,2% of the total sample they were patient of masculine sex e, in the casuistry of one another found study, that consisted of 50 patients, 56% were of masculine sex and 44% of the feminine one, results these similars to the gift estudo7,8. It was possible to observe, from this study, that the users had presented great prevalence of anemia, about 75%, being that the anemia of the normoctica type was most prevalent with 55% of the sample. The anemia in the chronic renal insufficiency is characteristically normocrmica, normoctica and with counting of red cells in the normal or diminished ssea marrow, had to its character hipoproliferativo5,9,10. The determinative factor of the present serious anemia in the chronic nefropatia is the deficiency of production of the eritropoetina for tubular epitlio 7,9. However, it has assumptions of that the urmicas toxins also inhibit the eritropoetina, and reduce the time of life of eritrcitos3,4.
Of this form, contributing for the understanding and the recognition of the essencialidade of sleep, sleeping well and being intent to the alterations of this process, that is basic to the life. Word-key: Paradoxical sleep REM or. Sleep NREM or of slow waves. System of Temporization. Quality of sleep. Riots of sleep.
Men and women are very different in character, in relation to each other, and indeed the perception of the world. The only thing than men and women are similar – they belong to the same species. They have since ancient times, has developed his own psychology. Man hunted to feed his family, protected. The woman, in turn, brought up children, till the soil, preparing a meal.