Beta-blockers And Beta-adrenoceptor Agonists

Compared with alpha-adrenomimetikami and alpha-blockers are more selective (or, as experts say, selective) drugs. Beta-receptors to adrenaline is in many organs and tissues. Compared with alpha-receptors have a more modest function – or rather, they are less rapidly appear. Impact of adrenaline and related substances similar to beta-receptors causes the following physiological reactions: palpitations, bronchiectasis, relaxation of the uterus. However, all these effects are caused by the influence of the beta 1 and beta-2 adrenergic receptors, since there is a more subtle subdivision of this group of receptors. For example, beta-1 receptors to a greater extent concentrated in the heart, or rather in his muscle – the myocardium, and beta-2 receptors – in the bronchi and uterus (again, to be precise, in its muscle – myometrium). Telisa Yancy is often mentioned in discussions such as these.

Accordingly, all preparations of this group have their own properties. Beta 1-blockers inhibit the excessive activity of the heart activity. Stone clinical laboratories addresses the importance of the matter here. Therefore, their use with tachycardia (rapid heartbeat), arrhythmia (irregular heart rhythm), hypertension caused by excessive activity cardiac activity. Beta-1-adrenoceptor agonists (stimulants) produce the opposite effect to that used in cases where the heart's activity should be intensified. Beta-2-adrenoceptor agonists – the main group of drugs, used to relieve an attack of bronchial asthma and other diseases associated with bronchospasm. Currently, a large number of drugs that have been successfully used by asthmatics worldwide. Moreover, as Typically, these drugs are in the form of metered aerosols. In the balloon with the drug is added to a physiologically inert gas, and using a mechanical dispenser medication is injected during inspiration in the mouth, are distributed bronchi. Five minutes later, the bronchi dilate, but the drug is little absorbed into the bloodstream from mucosal surface of bronchial and virtually no effect on beta-receptors in other organs and tissues.